ABT-089 / Pozanicline

Cholinergic / Nootropic

Attention/cognition positioning

Reading this compound Reference only

Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.

Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.

Mechanism & Use

Compound type: Small molecule
Primary mechanism: Alpha4beta2 nicotinic partial agonism
Primary market use: ADHD/cognition

Pharmacology

Molecular weight (Da): 254.3
Oral bioavailability: Oral; % not established
Half-life: ~4-8 h
Route tags: Route-dependent / verify
Evidence level: Clinical
Clinical status: Discontinued investigational
Value-for-money score: 4 / 10

Reported protocol signal

No popular protocol verified yet; keep as reference compound until protocol signal is added.

For orientation only. See disclaimer — always consult a licensed clinician before use.

Notes

Primarily receptor pharmacology

Sources

https://clinicaltrials.gov/