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BSemi-durableStandard research/education caution
CMP-0181
Approved for ovulatory dysfunction; male use off-label
Clomiphene / Clomifene
Endocrine / HPG-axis
Fertility induction and testosterone-axis stimulation positioning
Reading this compound Reference only
Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.
Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.
Mechanism & Use
- Compound type
- SERM
- Primary mechanism
- Hypothalamic ER antagonism increases GnRH/LH/FSH signaling
- Primary market use
- Fertility / endocrine
Pharmacology
- Molecular weight (Da)
- 405.96 base; 598.09 citrate
- Oral bioavailability
- Oral; readily absorbed
- Half-life
- Mixed isomers; ~5-7 d overall, zuclomiphene longer
- Route tags
- Route-dependent / verify
- Evidence level
- Approved/Clinical
- Clinical status
- Approved for ovulatory dysfunction; male use off-label
- Value-for-money score
- 6 / 10
Reported protocol signal
No popular protocol verified yet; keep as reference compound until protocol signal is added.
For orientation only. See disclaimer — always consult a licensed clinician before use.
Notes
Can create durable endocrine-axis recovery in selected contexts, but requires monitoring