Melatonin

Sleep / Circadian

Sleep timing and circadian support

Reading this compound Reference only

Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.

Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.

Mechanism & Use

Compound type: Indoleamine
Primary mechanism: MT1/MT2 receptor agonism
Primary market use: Sleep

Pharmacology

Molecular weight (Da): 232.3
Oral bioavailability: ~15%; variable
Half-life: ~20-60 min
Route tags: Route-dependent / verify
Evidence level: Human/supplement/drug
Clinical status: Supplement/approved forms
Value-for-money score: 8 / 10

Reported protocol signal

No popular protocol verified yet; keep as reference compound until protocol signal is added.

For orientation only. See disclaimer — always consult a licensed clinician before use.

Notes

Transient circadian signal

Sources

https://pubmed.ncbi.nlm.nih.gov/