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APotentially durableStandard research/education caution
CMP-0112
Research/supplement-adjacent
Piperlongumine
Senolytic / ROS stress
Potential senescent-cell apoptosis and anti-cancer/longevity research positioning
Reading this compound Reference only
Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.
Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.
Mechanism & Use
- Compound type
- Natural-product small molecule
- Primary mechanism
- Reactive oxygen species/proteotoxic stress amplification in senescent cells
- Primary market use
- Senolytic research
Pharmacology
- Molecular weight (Da)
- 317.34
- Oral bioavailability
- Oral; human F not established
- Half-life
- 1 to 2 hours
- Route tags
- Route-dependent / verify
- Evidence level
- Preclinical
- Clinical status
- Research/supplement-adjacent
- Value-for-money score
- 5 / 10
Reported protocol signal
No popular protocol verified yet; keep as reference compound until protocol signal is added.
For orientation only. See disclaimer — always consult a licensed clinician before use.
Notes
Promising natural product but systemic human PK and dosing are poorly established