Spexin
Longevity / senescence / mitochondrial
Aging biology, resilience, and durable cellular-function support
Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.
Mechanism & Use
- Compound type
- Longevity / geroprotector compound
- Primary mechanism
- Senescence, telomere, mitochondrial, or cellular stress pathway modulation
- Primary market use
- Longevity / senescence / mitochondrial
Pharmacology
- Molecular weight (Da)
- 1619.88
- Oral bioavailability
- Route-dependent / verify
- Half-life
- ~5–60 min parent peptide; analogs may be longer
- Route tags
- SubQ; Injectable; route-dependent
- Evidence level
- MCE product listing / research chemical signal
- Clinical status
- Research chemical/reference listing
- Value-for-money score
- 8 / 10
Reported protocol signal
No clean popular protocol found in uploaded sources; create as research/reference entry and verify before public protocol display.
For orientation only. See disclaimer — always consult a licensed clinician before use.
Notes
Spexin (Neuropeptide Q) is a selective agonist of galanin receptors GAL2 and GAL3 , and is a conserved peptide that functions as a neurotransmitter/neuromodulator and endocrine factor. Spexin can function through both central and peripheral actions. Spexin upregulates Beclin 1 to inhibit ferroptosis induced by excessive autophagy , reduces the uptake of long-chain fatty acids by adipocytes, and regulates energy metabolism by increasing lipid oxidation (e.g., reducing the respiratory exchange rat...