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CTransientPrescription / clinician-supervised
CMP-0457
Approved drug
Tadalafil
Vascular / Performance
Improves erectile function and pulmonary/vascular hemodynamics; may support exercise tolerance in specific vascular contexts
Reading this compound Reference only
Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.
Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.
Mechanism & Use
- Compound type
- Small molecule drug
- Primary mechanism
- PDE5 inhibition increasing cGMP signaling
- Primary market use
- ED / PAH / vascular performance
Pharmacology
- Molecular weight (Da)
- 389.41
- Oral bioavailability
- Oral; absolute F not determined
- Half-life
- ~17.5 h
- Route tags
- Oral
- Evidence level
- Approved
- Clinical status
- Approved drug
- Value-for-money score
- 8 / 10
Reported protocol signal
Prescription use; common ED dosing 5 mg daily or 10–20 mg as needed.
For orientation only. See disclaimer — always consult a licensed clinician before use.
Notes
High value due oral route, long duration, generic availability, and clear QoL benefit in indicated use