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CTransientStandard research/education caution
CMP-0459
Approved
Tamoxifen
Endocrine / SERM
ER-positive breast cancer treatment/prevention and endocrine modulation
Reading this compound Reference only
Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.
Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.
Mechanism & Use
- Compound type
- SERM
- Primary mechanism
- Estrogen receptor modulation; ER antagonist in breast tissue
- Primary market use
- Oncology / endocrine
Pharmacology
- Molecular weight (Da)
- 371.5 base; 563.6 citrate
- Oral bioavailability
- Oral; high
- Half-life
- ~5-7 d; active metabolites longer
- Route tags
- Route-dependent / verify
- Evidence level
- Approved
- Clinical status
- Approved
- Value-for-money score
- 5 / 10
Reported protocol signal
No popular protocol verified yet; keep as reference compound until protocol signal is added.
For orientation only. See disclaimer — always consult a licensed clinician before use.
Notes
Durable disease outcomes possible, but pharmacologic ER modulation requires ongoing dosing