Tesofensine + Metoprolol

Thermogenic / Appetite

Weight-loss positioning with HR mitigation

Reading this compound Reference only

Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.

Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.

Mechanism & Use

Compound type: Small molecule combination
Primary mechanism: Monoamine reuptake inhibition + beta-blockade
Primary market use: Obesity

Pharmacology

Molecular weight (Da): Combination / variable
Oral bioavailability: High
Half-life: Teso ~9 d; metoprolol ~3-7 h
Route tags: Route-dependent / verify
Evidence level: Clinical
Clinical status: Investigational
Value-for-money score: 6 / 10

Reported protocol signal

Oral: 500 mcg daily in the early morning (Tailor Made Compounding Catalog, Jay Campbell) (some start at a smaller dose)

For orientation only. See disclaimer — always consult a licensed clinician before use.

Notes

Requires ongoing dosing

Sources

https://clinicaltrials.gov/