Tesofensine

Thermogenic / Appetite

Appetite reduction and weight-loss positioning

Reading this compound Reference only

Information below is educational. Dosing, mechanisms and status fields are compiled from the source list at the bottom of this page — always verify against a licensed clinician before use.

Reference-only summary of publicly discussed or source-listed patterns. Not medical advice and not a personal recommendation.

Mechanism & Use

Compound type: Small molecule
Primary mechanism: Triple monoamine reuptake inhibition
Primary market use: Obesity

Pharmacology

Molecular weight (Da): 293.8
Oral bioavailability: High
Half-life: ~9 d
Route tags: Route-dependent / verify
Evidence level: Clinical/approved some markets
Clinical status: Investigational/approved varies
Value-for-money score: 6 / 10

Reported protocol signal

Oral: 500 mcg daily in the early morning (Tailor Made Compounding Catalog, Jay Campbell) (some start at a smaller dose)

For orientation only. See disclaimer — always consult a licensed clinician before use.

Notes

Requires ongoing dosing

Sources

https://clinicaltrials.gov/